The project started in 2013 as a research which aimed at identification of mechanisms of calcification using advanced bioinformatics approaches and molecular biology methods. The project was developed in the frame of the scientific program called FOIRMYS (first open institute of regenerative medicine for young scientists). At the end of our team research in FOIRMYS we published a paper in Rejuvenation Research. The project had a continuation, in which we analysed the transcriptomics data obtained from GEO database.